Late-Breaking Clinical Trials
Late-Breaking Clinical Trials for presentation at ACC.10 and i2 Summit have been selected! The impressive line-up of cutting-edge science includes the results of EVEREST II, comparing percutaneous repair of mitral valve leakage to surgical repair; the STOP-AF trial of cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation; and a five-year follow-up of the PASSION Trial of Paclitaxel-eluting stents vs. bare-metal stents. Don’t miss these trials and more.
Late-Breaking Clinical Trials I: General Cardiology
Session 3010
ACC/i2 Joint Session
Sunday, Mar 14, 2010, 8:00 a.m. – 9:30 a.m.
Georgia World Congress Center, Murphy Ballroom
- Effects of Combination Lipid Therapy on Cardiovascular Events in Type 2 Diabetes Mellitus: The ACCORD Lipid Study
- Effects of Intensive Blood Pressure Control on Cardiovascular Events in Type 2 Diabetes Mellitus: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Blood Pressure Trial
- Rethinking Lower BP Goals for Diabetics with Documented Coronary Artery Disease: Findings from the INternational VErapamil SR - Trandolapril STudy (INVEST)
- The Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial
- 3010-14: Primary Safety and Efficacy Endpoints of the EVEREST II Randomized Clinical Trial
Late-Breaking Clinical Trials II: Cardiac Arrhythmias
Session 3015
ACC/i2 Joint Session
Monday, Mar 15, 2010, 8:00 a.m. – 9:30 a.m.
Georgia World Congress Center, Murphy Ballroom
- Cryoballoon Ablation of Pulmonary Veins for Paroxysmal Atrial Fibrillation: First Results of the North American Arctic Front Stop-AF Clinical Trial
- Rate Control Efficacy in Permanent Atrial Fibrillation: a Comparison Between Lenient Versus Strict Rate Control in Patients With and Without Heart Failure. The RACE II Study
- The Impact of Remote Monitoring with Automatic Clinician Notifications on the clinical care of ICD and CRT-D Patients
- A Randomized Clinical Trial of Three Doses of a Long-Acting Oral Direct Factor Xa Inhibitor Betrixaban in Patients with Atrial Fibrillation
- Catheter Ablation vs. Antiarrhythmic Drug Therapy for Atrial Fibrillation: First Results of the CABANA Pilot Study
Late-Breaking Clinical Trials III: Interventional Cardiology
Session 3016
ACC/i2 Joint Session
Monday, Mar 15, 2010, 10:30 a.m. – Noon
Georgia World Congress Center, Murphy Ballroom
- Randomized All-comer Comparison of Zotarolimus-eluting and Sirolimus-eluting Coronary Stents: 18-month Follow-up in the SORT OUT III Trial
- Randomized Trial of a Polymer-Free Dual Drug-Eluting Stent versus Polymer-Based Cypher and Endeavor Drug-Eluting Stents - Two-year Clinical and Angiographic Outcomes
- First Report of the PERSEUS Randomized Controlled Trial Comparison of a Novel Platinum-Chromium, Thin-Strut TAXUS Element Stent Versus the TAXUS Express Stent in de novo Coronary Stenoses
- Randomized Trial Evaluating the Efficacy of Cilostazol on Ischemic Vascular Complications after Drug-eluting Stent Implantation for Coronary Heart Disease : Influence of Cilostazol-based triple anti-platelet therapy on Ischemic Complication after drug-eluting stent implantation (CILON-T) study
- Optimal Duration of Dual Antiplatelet Therapy After Drug-Eluting Stents Implantation: A Randomized, Multi-Center Trial
Late-Breaking Clinical Trials IV
Session 3019
ACC/i2 Joint Session
Tuesday, Mar 16, 2010, 8:00 a.m. – 9:30 a.m.
Georgia World Congress Center, Murphy Ballroom
- Effect of Genotyping Warfarin Patients on Outcomes: Results from The National Community-based Medco-Mayo Warfarin Effectiveness Study (MM-WES)
- The Diuretic Optimization Strategies Evaluation (DOSE) Study: A Randomized, Double Blind, Placebo-controlled Trial Of Diuretic Strategies In Acute Decompensated Heart Failure
- Effect of the Direct Renin Inhibitor Aliskiren on Left Ventricular Remodeling Following Myocardial Infarction with Left Ventricular Dysfunction: ASPIRE
- Effects of Clinical Characteristics and Treatments on Gender Difference in Outcomes after Acute Myocardial Infarction: A Propensity Score-Matched Analysis
- Influence of Reduction of Left Ventricular Volume on Outcome After Coronary Artery Bypass Grafting With or Without Surgical Ventricular Reconstruction
Late-Breaking Clinical Trials V: Interventional Cardiology
Session 3020
ACC/i2 Joint Session
Tuesday, Mar 16, 2010, 10:30 a.m. – Noon
Georgia World Congress Center, Murphy Ballroom
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Randomized Comparison of Angiojet Rheolytic Thrombectomy Before Direct Infarct Artery Stenting to Direct Stenting Alone in Patients with Acute Myocardial Infarction: the Jetstent Trial
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Long-term Outcome after Drug-Eluting versus Bare-Metal Stent Implantation in Patients with ST-Elevation Myocardial Infarction. Three-year follow-up of the DEDICATION Trial
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Five Year Follow-up After Primary Percutaneous Coronary Intervention With A Paclitaxel-eluting Stent Versus A Bare-metal Stent In Acute ST-segment Elevation Myocardial Infarction. A Follow-up Study Of The PASSION-Trial
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Ticagrelor Versus Clopidogrel In Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery: Results From The PLATO Trial
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A Randomized Trial Radial Artery Grafts versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery: VA Cooperative Study
Be sure to also attend the new “Trialist Is In” round-table sessions where you’ll get to meet-and-greet the trialists and ask questions in an informal setting, Sunday and Monday, from 3:30 p.m. – 4:30 p.m. in Hall B2.
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